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Tropical Fish Research

Tropical Fish Health Benefits – Further Zebra Danio Research

We have had a few articles previously outlining the increasing importance of using tropical fish in the study of diseases and providing health benefits that are above and beyond their stress reducing capacity when viewed.  Zebra Danio research has become a very important laboratory research tool. In a recently published story from Wesleyan University, researchers have used the Danio rerio and some mutant variants to further understanding and knowledge on a particular gene found in both these fish and humans as well.  The gene, tbx6 has been known to deal with the development of muscles and stem cells, but its role has not been well understood.  This Zebra Danio research is aimed at finding the ways that these genes operate, and the future conclusions could have great impact on preventing or treating people with serious muscular disorders.   The report by the Hartford Courant states:

Now, this freshwater tropical fish may have helped Wesleyan researchers uncover one of the mysteries at the root of muscular dystrophy and other diseases that affect human musculature. A recent study led by Dr. Stephen DeVoto, a biology professor at Wesleyan, shows how a gene known as tbx6 plays a major role in the development of muscle and stem cells as well as the development of vertebrae.

Further Zebra Danio Research is needed

Zebra Danio Danio rerio

Zebra Danio research has become an important tool in the medical field

The findings are still very much in the initial stages.  It is, however, heartening to know that at least a bit of light has been shown on the ways that a previous gene with unknown capabilities has been identified as controlling some of the muscular and bone development in the zebra danio.  Mutant strains of the fish without this gene had spinal deformities and even fused spines.  This Zebra Danio research has shed some light on the operation and control that the tbx6 gene exerts during fetal development.  It may not lead to a cure for Muscular Dystrophy in human patients, but further research may discover ways to prevent the problem form occurring in the first place.

The more we find out about these fish,it seems the greater the knowledge we have abut our own situations as well


Steve Pond, of Tropical Fish Aquarist, has kept fish both personally and professionally for over 50 years.  He writes regularly on the wide range of current topics that are important to people who keep tropical fish tanks as a passion and a hobby.

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About blueram

Steve Pond, of Tropical Fish Aquarist, has kept fish both personally and professionally for over 50 years.  He writes regularly on the wide range of current topics that are important to people who keep tropical fish tanks as a passion and a hobby.

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  1. Danio zebras | FirstloveconsuSeptember 6, 2012 at 12:23 amReply

    […] Further Zebra Danio Research – Tropical Fish Aquarist […]

  2. TuyaOctober 7, 2012 at 1:48 amReply

    Possibly stressed from being pcekid on.She also could be pregnant.Some fish also get stressed by sudden water changes.Common symptoms of stress include: Fish stays near the surface gasping for breath, indicating that it has trouble getting enough oxygen (the concentration of dissolved oxygen is highest near the water’s surface). Possible causes include low oxygen concentration due to poor water circulation, toxins that have damaged its gills, high ammonia or nitrite levels, etc.Fish won’t eat, or doesn’t eat as aggressively as in past.Fish stays hidden continuously and won’t come out where it can be seen. Possible causes: aggressive fish, insufficient cover (e.g., plants, wood, etc.) to make fish feel safe while swimming about.Fish has nicked fins, open wounds that don’t seem to heal. Possible cause: fish is target of aggression. Normally, minor nicks and cuts heal quickly. If they don’t, stress levels may be suppressing the fish’s immune system.Fish has disease (parasites, fungus, etc.) Of course, the disease itself is a major problem. But in most cases, a healthy fish’s immune system keeps it from getting sick in the first place. Thus, getting sick is a sign that the fish is in a stressed state (or had been until recently). Tips on keeping your fish from being stresses:-Keep in mind that if your fish is sick, it’s stressed. And stressed fish are more likely to get sick.-Know that a fish whose wounds don’t heal is having problems. Make sure it doesn’t have parasites. Watch to see if it’s the victim of a bully in the tank. Make sure that there are plenty of hiding places.-Make sure you’re giving it a variety of foods and that it isn’t having to compete to eat if your fish has lost its appetite.-Give your fish space. Make sure that the tank is not too crowded. Like people, fish need their space.-Be sure that the species in your tank are compatible.-Keep the tank at optimum temperatures and the equipment in good condition. Fish need oxygen; some fish are more tolerant of low-oxygen water than others. A fish that stays near the top of the tank and gasps for breath is telling you that it’s having trouble breathing. Check the ammonia and nitrite levels, the filters, and the fish’s gills.-Never add untreated tap water to the tank. Chlorine and chloramine are toxic to fish.-Keep the tank and filters clean. Poor water quality, especially levels of ammonia and nitrites, and the pH can really put a fish in a bind.-Find out what your fish like. Some prefer hard water over soft, some prefer acid over alkaline, and some do better with a little bit of salt in the water. Are they solitary or school fish?-Make sure the tank doesn’t get too small for its occupants. Crowding can lead to increased aggression.-Use extreme caution when adding medication to the tank water. Any change you make to the chemistry is going to affect everything living in it.

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